What's the Best Treatment for Toenail Fungus Today?

I'm looking for a best and effective treatment for my brother's toenail fungus. I heard that many new treatment nowadays is proven effective to remove fungus. The only treatments I've knew is the Tea Tree Oil, Vick's Vapor Rub, Laser procedure and the newbie, Fungusil. Help me guys! My brother were so desperate to remove his toenail fungus. Thanks!